The mission of the Charlotte Chamber of Commerce is to promote a climate that is favorable for the vibrancy of the community and mutual success of all current and potential Charlotte area businesses and organizations through collaboration, leadership and service.

The Chamber of Commerce of the United States of America with National Headquarters in Washington DC certificate of Organization Membership states "This certifies that the Charlotte Chamber of Commerce having been duly elected on November 30, 1945, an organization member of the Chamber of Commerce of the United States of America. The Charlotte Chamber incorporated as a nonprofit corporation on July 26, 1965.