Built in 1878 for Thomas and Mina Slattery, grandparents of Dr. George Parker of Delaware, the residence was purchased by William Henry Nash and his wife Emeline in 1885 and it remained in the Nash family until 1954 when Miss Pauline Nash presented the house to the Delaware County Historical Society. Eugene Nash added the front porch after 1916.

The Nash House is generally furnished in the Victorian period. Rooms on display include the parlor, music room, dining room, gentleman's study, children's room, bedroom, and kitchen, which was remodeled to match the late 1930's style.