Weatherford  is the birthplace and childhood home of astronaut and flight pioneer General Thomas P. Stafford. The Stafford Air & Space Museum houses an amazing collection of air and space exhibits featuring flown-in-space artifacts and historically important aircraft.

The Stafford Air & Space Museum, founded in 1981, had humble beginnings and started with a few memorabilia items and artifacts donated to the airport and displayed in a cabinet in the lobby. A museum architect was engaged to build two rooms to display the life and career of Thomas Stafford, which was completed in 1993. In 1999, a 12,000 square ft. addition was constructed to properly house some of the large artifacts that had been collected.  A major addition was constructed in 2001 to include a large series of aeronautical and space artifacts purchased from a private collection. The multi-function use Apollo Room, gift shop, offices, rest rooms, and foyer area were added in 2003. The 8,700 square feet addition in the Hubble Gallery classroom and exhibit area for the Apollo, Gemini, and Space Shuttle programs was added in 2006. The museum has expanded to 40,000 square feet with the addition of the Rose and Tom Luczo Educational Center completed in February 2009.

The Stafford Air & Space Museum is the premier museum of its type in the southwestern area of the United States. Currently, the museum houses many of the best flight exhibits and space artifacts available. Its mission is to promote the adventurous spirit of flight and space travel, while encouraging primarily science and mathematics educational excellence. The Board of Directors, Ex- Officio Board Members, Executive Directors, staff, donors and volunteers are dedicated to making the Stafford Air & Space Museum the premier interactive air and space flight discovery center in the Southwest. The museum is owned and operated by the City of Weatherford, Oklahoma and is a 501(c)3 charitable organization since 1996. The Stafford Air & Space Museum is supported by General Thomas P. Stafford, as well as public, private and corporate donations.