Enjoy Your Stay in Roanoke, VA at Our Hotel! Nestled in the heart of Virginia’s Blue Ridge Mountains, the Holiday Inn® Tanglewood - Roanoke has a picturesque location in Roanoke's upscale south side. We are located off Route 220/I-581 and close to I-81. This central and safe location makes us attractive to guests working in and visiting Downtown Roanoke and Historic Grandin. The Salem Civic Center, Moyer Sports Complex, Berglund Center and Carilion Hospital are all within minutes of our hotel making local travel a breeze. Discovery awaits as we are just two miles from the Blue Ridge Parkway, minutes away from shopping, breweries, and a plethora of local dining favorites. For those looking to further explore, the Taubman Museum, Mill Mountain Star, Zoo, and the famous Blackdog Salvage are worth a visit! Guests can travel a short distance to the D-Day Memorial, Explore Park, Virginia Tech University, VMI, Washington, and Lee, Liberty and Ferrum, and Martinsville Speedway! Our hotel's warm and welcoming team will make any traveler feel right at home. Guests enjoy complimentary use of our fitness and business centers and seasonal, outdoor heated pool! Our sleeping rooms greet you with plush amenities, mini-fridge, microwave, and Keurig, along with free Wi-Fi and well-lit parking. When the day has winded down, don’t forget to stop by our onsite restaurant, Elephant Walk, for daily specials!