From its headwaters to Camas Creek, the North Fork of the John Day River is one of the most important rivers in northeast Oregon for the production of anadromous fish. Wildlife found along the river's corridor include mule deer, elk, and black bears, along with peregrine falcons and bald eagles. Recreation opportunities include hunting, fishing, sightseeing, horseback riding, hiking, snowmobiling, skiing, camping, and whitewater rafting

The John Day River system is fortunate to have designation under two important river preservation programs: the National Wild and Scenic Rivers Act and the Oregon Scenic Waterways Act. Together, these two acts, one a federal program and one a state program, provide the best protection available today for the natural, scenic, and recreational values of our river environments.