The Neshoba County School District is a public school district based in Neshoba County, Mississippi (USA).

The district does not includes the communities of Pearl River and Tucker, the Neshoba County portion of Bogue Chitto, which are privately owned and operated by the sovereign nation of the Mississippi Band of Choctaw Indians.

There were a total of 3,079 students enrolled in the Neshoba County School District during the 2006-2007 school year. The gender makeup of the district was 51% female and 49% male. The racial makeup of the district was 20.88% African American, 69.28% White, 8.77% Native American, 0.75% Hispanic, and 0.32% Asian. 45.6% of the district's students were eligible to receive free lunch.

In the Neshoba County School District, 14% of students have an IEP (Individualized Education Program).  An IEP is a written plan for students eligible for special needs services.