Worshippers have met on this spot continuously since 1685, when the First Parish in Sherborn was founded with the Reverend Daniel Gookin called as first minister. Reverend Gookin's gravestone, recently discovered and restored, is now housed and displayed within the sanctuary. Along with John Eliot of Natick, Reverend Gookin also ministered to the local Natick Praying Indians, especially during the Nipmucs' exile to Deer Island in the 17th Century during King Philips War.

The present structure, the third on this site, was built in 1830 and is listed with the National Register of Historic Places. Built in Greek Revival style, its dominant feature is its octagonal steeple, which blew off during a 1938 hurricane and was replaced as faithfully as possible in 1940.

When Unitarianism flowered in 19th century New England, the First Parish congregation claimed that faith in 1830, and a Trinitarian faction split away. In 1897, in nearby Natick, the Natick Unity Church was founded in memory of Sarah Allen Cooney, its principal advocate of Unitarianism. In 1967, the Natick church building was destroyed by fire. The Sherborn and Natick Unitarian Universalist churches merged in 1977, creating the church as we know it today.We are a caring community dedicated to spiritual exploration through reflection, education, action and
service.